Vinod Vogirala

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Electron Microscope Scientist at the electron Bio-Imaging Centre (eBIC)

Vinod joined eBIC in November 2019.

Email: vinod.vogirala@diamond.ac.uk
Tel: +44 (0) 1235 77 8007

Latest Publications

Dr Vinod Vogirala obtained his Ph.D. from the department of Molecular Biology and Biophysics, ETH Zurich, Switzerland. He then worked as a research fellow at the School of Biological Sciences in NTU, Singapore.

In November 2019, Vinod joined the eBIC team as a Senior EM Support Scientist and in November 2021 he has been promoted to an Electron Microscope Scientist.

His research interest is in structural biology, especially in single particle cryo-electron microscopy.

Vergara-Cruces Á, Pramanick I, Pearce D, Vogirala VK, Byrne MJ, Low JKK, Webster MW. (2024) Structure of the plant plastid-encoded RNA polymerase. Cell. Feb 29;187(5):1145-1159.e21. doi: 10.1016/j.cell.2024.01.036. PMID: 38428394.

Zhao X, Vogirala VK, Liu M, Zhou Y, Rhodes D, Sandin S, Yan J. (2024) Exploring TRF2-Dependent DNA Distortion Through Single-DNA Manipulation Studies. Commun Biol. Feb 3;7(1):148. doi: 10.1038/s42003-024-05838-x. PMID: 38310140; PMCID: PMC10838314.

Soman A, Wong SY, Korolev N, Surya W, Lattmann S, Vogirala VK, Chen Q, Berezhnoy NV, van Noort J, Rhodes D, Nordenskiöld L. (2022) Columnar structure of human telomeric chromatin. Nature. Sep;609(7929):1048-1055. doi:10.1038/s41586-022-05236-5. Epub 2022 Sep 14. PMID: 36104563.

Sheng Y, Harrison PJ, Vogirala V, Yang Z, Strain-Damerell C, Frosio T, Himes BA, Siebert CA, Zhang P, Clare DK. (2022) Application of super-resolution and correlative double sampling in cryo-electron microscopy. Faraday Discuss. Nov 8;240(0):261-276. doi: 10.1039/d2fd00049k. PMID: 35938521; PMCID: PMC9642007.

Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH. (2022) Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes. Proc Natl Acad Sci USA. Aug 2;119(31):
e2205412119. doi: 10.1073/pnas.2205412119. Epub 2022 Jul 15. PMID: 35858383; PMCID: PMC9351521.

Wang S, Vogirala VK, Soman A, Berezhnoy NV, Liu ZB, Wong ASW, Korolev N, Su CJ, Sandin S, Nordenskiöld L. (2021) Linker histone defines structure and self-association behaviour of the 177 bp human chromatosome. Sci Rep. Jan 11;11(1):380. doi: 10.1038/s41598-020-79654-8. PMID: 33432055; PMCID: PMC7801413.

Huo J, Bas AL, Ruza RR, Duyvesteyn HME, Mikolajek H, Malinauskas T, Tan TK, Rijal P, Dumoux M, Ward PN, Ren J, Zhou D, Harrison PJ, Weckener M, Clare DK, Vogirala VK, Radecke J, Moynié L, Zhao Y, Gilbert-Jaramillo J, Knight ML, Tree JA, Buttigieg KR, Coombes N, Elmore MJ, Carroll MW, Carrique L, Shah PNM, James W, Townsend AR, Stuart DI, Owens RJ, Naismith JH. (2021) Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2. Nat Struct Mol Biol. Mar;28(3):326. doi: 10.1038/s41594-021-00566-w. (2020) Erratum for: Nat Struct Mol Biol. Sep;27(9):846-854. doi: 10.1038/s41594-020-0469-6. PMID: 33536566; PMCID: PMC7857722.

Chua EY, Vogirala VK, Inian O, Wong AS, Nordenskiöld L, Plitzko JM, Danev R, Sandin S.(2016) 3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM. Nucleic Acids Res. Sep 30;44(17):8013-9. doi:10.1093/nar/gkw708. Epub 2016 Aug 25. PMID: 27563056; PMCID: PMC5041491.

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