Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy I03 Contact
Beamline Phone Number:
+44 (0) 1235 778707
Acting Principal Beamline Scientist:
Dave Hall
Tel: +44 (0) 1235 778926
E-mail: david.hall@diamond.ac.uk
Science Group Leader
Dave Hall
Email: david.hall@diamond.ac.uk
Tel: +44 (0) 1235 778926
I03 MX
Status: Operational
Beamsize: 90 µm x 20 µm
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
These publications are based on data gathered on beamline I03. If you are aware of any errors or publications that should be listed here, please send details to publications@diamond.ac.uk.
8 items found for 2026 [total: 2310]
Structure, function, and applications of two novel phage recombinases from extreme environments Nucleic Acids Research, 54 Feb 2026 DOI: 10.1093/nar/gkag069
Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐ CoA lyase Febs Open Bio, 11 Jan 2026 DOI: 10.1002/2211-5463.70199
Discovery of SY-589, a highly potent and orally bioavailable Polθ helicase inhibitor for the treatment of HR-deficient tumors Journal Of Medicinal Chemistry, Jan 2026 DOI: 10.1021/acs.jmedchem.5c02689
Journal Paper I03-Macromolecular Crystallography
Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors Nature Communications, 16 Jan 2026 DOI: 10.1038/s41467-026-68319-1
A hooker oxygenase archetype in polyketide biosynthesis challenging the Baeyer–Villiger monooxygenase paradigm Journal Of The American Chemical Society, Jan 2026 DOI: 10.1021/jacs.5c21759
Modulation of the 14-3-3σ/C-RAF “auto” inhibited complex by molecular glues Journal Of The American Chemical Society, Jan 2026 DOI: 10.1021/jacs.5c12622
Cell wall target fragment discovery using a low‐cost, minimal fragment library Febs Letters, 12 Jan 2026 DOI: 10.1002/1873-3468.70281
Molecular structure of the ESCRT-III-based archaeal CdvAB cell division machinery Proceedings Of The National Academy Of Sciences, 123 Jan 2026 DOI: 10.1073/pnas.2525941123
- Emma Tarrant, Isabel G. Cormack, Charlotte E. Hunter, Olesia Werbowy, Sebastian Dorawa, Lei Wang, Ida Helene Steen, Ruth-Anne Sandaa, Elísabet Eik Guðmundsdóttir, Bernd Ketelsen-Striberny, Anna-Karina Kaczorowska, Tadeusz Kaczorowski, Ehmke Pohl, Stefanie Freitag-Pohl, "Structure, function, and applications of two novel phage recombinases from extreme environments", Nucleic Acids Research, 54 (2026), DOI: 10.1093/nar/gkag069
- Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder, "C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐ CoA lyase", Febs Open Bio, 11 (2026), DOI: 10.1002/2211-5463.70199
- Chongxun Ge, Dazhi Feng, Song Shi, Xuzhen Tang, Yaqi Cui, Song Liu, Yunyue Wang, Shuangtian Tang, Xinnan Li, Xianqiang Sun, Daopeng Yuan, Jinyi Xu, Hu He, Hong Yao, "Discovery of SY-589, a highly potent and orally bioavailable Polθ helicase inhibitor for the treatment of HR-deficient tumors", Journal Of Medicinal Chemistry (2026), DOI: 10.1021/acs.jmedchem.5c02689
- Daniel A. Bonsor, Lorenzo I. Finci, Jacob R. Potter, Lucy C. Young, Vanessa E. Wall, Ruby Goldstein De Salazar, Katie R. Geis, Tyler Stephens, Joseph Finney, Dwight V. Nissley, Frank Mccormick, Dhirendra Simanshu, "Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors", Nature Communications, 16 (2026), DOI: 10.1038/s41467-026-68319-1
- Heiner G. Weddeling, Sven T. Sowa, Elena Bialas, Sven Reese, Christian Merten, Markus Lill, Andreas Bechthold, Robin Teufel, "A hooker oxygenase archetype in polyketide biosynthesis challenging the Baeyer–Villiger monooxygenase paradigm", Journal Of The American Chemical Society (2026), DOI: 10.1021/jacs.5c21759
- Markella Konstantinidou, Holly R. Vickery, Marloes A. M. Pennings, Johanna M. Virta, Shu Yue Luo, Emira J. Visser, Sean D. Bannier, Mrudula Srikanth, Sabine Z. Cismoski, Lucy C. Young, Maxime C. M. Van Den Oetelaar, Frank Mccormick, Christian Ottmann, Luc Brunsveld, Michelle R. Arkin, "Modulation of the 14-3-3σ/C-RAF “auto” inhibited complex by molecular glues", Journal Of The American Chemical Society (2026), DOI: 10.1021/jacs.5c12622
- Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C. Dorfmueller, Daniel M. F. Van Aalten, "Cell wall target fragment discovery using a low‐cost, minimal fragment library", Febs Letters, 12 (2026), DOI: 10.1002/1873-3468.70281
- Tina Drobnič, Ralf Salzer, Tim Nierhaus, Margaret Ke Xin Jiang, Dom Bellini, Astrid Steindorf, Sonja-Verena Albers, Buzz Baum, Jan Lowe, "Molecular structure of the ESCRT-III-based archaeal CdvAB cell division machinery", Proceedings Of The National Academy Of Sciences, 123 (2026), DOI: 10.1073/pnas.2525941123
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