Specification

Available energy

DMM 5 x 10^-3 ΔE/E

< 10 x 10 μm² 

DMM > 2 x 10¹³ ph/s

Users mark objects in the synchweb interface, and queue points for data collection. Alternatively CHIMP software can automatically identify and target crystals for data collection, by machine learning.

All other task a carried out by the beamline. The system loads plates storage to goniometer, images wells, finds samples and collects data. Data are processed and grouped automatically. Users are notified when data is completed so that they can review their results. 

Grid scans and <60º oscillation data collections are performed at 500 Hz. Imaging and centering each well take around 2 mins so the beamline is able to:

- Screen 500 1000 μm² regions of interest in 24 hours.

- Collect 4000 individual oscilation scans in 24 hours.

Datasets from crystals collected in the same well, and/or in designated groups will be automatically processed together, which can result in complete data sets. This can then be further analysed using intensity-based clustering that can separate data into different structures - this automaticaly runs after data collection. 

Descriptions of Ligands can be added, using a SMILES code, with an automated Ligand-Fitting pipeline running - triggered in this case.