• Diamond Home page
  • About
  • For Users
  • Public
  • Industry
  • Instruments
  • Careers
  • More Show more menu items
Search

About Diamond

  • About Diamond
  • About Synchrotron
  • News and Features
  • Events
  • Contact Us
  • FAQ

For Users

  • Apply for beamtime
  • User guide
  • Diamond Users Commitee
  • FAQ

Industry

  • Techniques Available
  • Industry Research
  • Industry Case Studies
  • News
  • Meet the Industry Team

Science

  • Research
  • Computing
  • The Machine
  • Publications
  • Research Expertise
  • Membrane Protein Laboratory
  • Additional Facilities

Instruments

  • Biological Cryo-Imaging
  • Crystallography
  • Imaging and Microscopy
  • Macromolecular Crystallography
  • Magnetic Materials
  • Soft Condensed Matter
  • Spectroscopy
  • Structures and Surfaces

Careers

  • Vacancies
  • Info for applicants
  • Company Benefits
  • Apprenticeships
  • PhD Studentships
  • Work Placement

Public

  • News
  • How Diamond Works
  • Multimedia
  • Features
  • Visits Us
  • For School

Procurement

  • Non-OJEU Tender Notices
  • OJEU PINs
  • OJEU Tender Notices
  • Registration Form

Software & Tools

  • Publications Database
  • iSpyB
  • User Administration System

Main Content

Instruments
Sub-navigation
  • Instruments
  • Techniques
  • Capabilities

In This Section

Sub Navigation
  • Diffraction
  • Imaging
  • Microscopy
    • Cryo X-ray Microscopy
    • Cryo-EM
    • FIBSEM: Cryo Focused Ion Beam Scanning Electron Microscopy
    • Topography
    • CLEM: Correlative Light Electron Microscopy
    • CLXM: Correlative Light X-ray Microscopy
    • PEEM: PhotoEmission Electron Microscopy
  • Scattering
  • Spectroscopy

Instruments by Science Group

Macromolecular
Crystallography
Soft Condensed
Matter
Imaging and
Microscopy
Biological
Cryo-Imaging
Magnetic
Materials
Structures and
Surfaces
Crystallography
Spectroscopy
  1. Instruments
  2. Techniques
  3. Microscopy
  4. Cryo-EM

Cryo-EM

Cryo-electron microscopy (cryo-EM) is the investigation of a sample with an electron microscope at cryogenic temperatures. It involves a beam of electrons fired at a frozen protein, the scattered electrons are collected and detected in roder to work out the structure of the frozen sample.

Relevant Instrument(s)

eBIC

eBIC provides scientists with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy, for both single particle analysis and cryo-tomography. Currently eBIC houses four Titan Krios microscopes, a Talos Arctica, an Aquilos cryo-FIB/SEM and a cryo-CLEM microscope.

More information
Accelerating Voltages: 3-30, 200 & 300 kV
Cryo-EM: Cryo Electron Microscopy Cryo-ET: Cryo Electron Tomography Imaging Electron Microscope Electron Crystallography FIBSEM: Cryo Focused Ion Beam Scanning Electron Microscopy Microscopy Remote Access
  • Contact Us
  • About Diamond Light Source
  • Procurement
  • Supply Chain Transparency
  • Cookie Policy
  • Website Terms of Use
  • Privacy Notice

Diamond Light Source

Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

Follow us on Facebook Follow us on Linkedin Follow us on Instagram Follow us on Bluesky

Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE

See on Google Maps

Copyright © Diamond Light Source. Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd

Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.

feedback