Manikandan Karuppasamy

profilephoto

Industrial Liaison Scientist, Cryo-Electron Microscopy

Email: industry@diamond.ac.uk
Tel: +44 (0)1235 394195

Manikandan Karuppasamy joined eBIC for Industry’s team of cryo-EM scientists early in 2022. He assists industrial clients in screening, collecting high-resolution single-particle cryo-EM data, and solving difficult structures.

He has a background in structural biology, having worked in academia to understand the biological functions of several macromolecular complexes using both crystallography and cryo-EM.

He gained his PhD in protein crystallography at the Indian Institute of Science in Bangalore where he identified the molecular factors responsible for the adaptation of temperature and salt stability of xylanases in extreme environments from their atomic structures.

Following this, he joined EMBL-Hamburg as a Humboldt Research Fellow and deciphered X-ray crystal structures of Leucine biosynthesis pathway enzymes of Mycobacterium tuberculosis before moving to EMBL-Grenoble to apply cryo-EM techniques to solve structures of pharmaceutically important macromolecular complexes.

His research interests centre on solving challenging smaller pharmaceutical targets and membrane proteins by cryo-EM and he has a keen interest in contributing to method development for faster screening of grids for high-resolution data collection.

Diamond Light Source

Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

Copyright © 2022 Diamond Light Source

 

Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE

See on Google Maps

Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd

Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.

feedback