cryo-EM services

Our dedicated Industry labs support users in optimising their samples and mounting them onto cryo-EM grids. Using our in-house Vitrobot, samples are vitrified and then screened on the dedicated Industry Glacios microscope to assess their suitability for high-resolution imaging on the Krios. This process enables users to refine their samples in a cost-effective way before progressing to more valuable microscope time.

Our data collection service comes with a range of options to ensure you get the most out of your experiment.  We provide preliminary data collection through our in-house Glacios and high-throughput data collection once suitable candidates have been identified. Our highly qualified and experienced team of cryo-EM specialists will help you to get started with your experiment and will be available for technical support during your experiment. They will help you to select the most appropriate approach to reach your research goals. You may wish our team to perform the experiment on your behalf or would prefer to perform the research yourself or with your own team; either way, we have a wide range of access options, including remote access and mail-in] to suit your needs.

We can provide support at each step of the cryo-EM experiment from freezing your samples, screening them, through to data collection and structure solution.  Our highly qualified and experienced staff will assess your project’s suitability for cryo-EM and can conduct all the steps of the EM pipeline on your behalf, advising on the best course of action at each decision point  whilst leaving you in control of overall project direction.  This includes freezing and screening your samples, collecting data, and solving your structures. It all depends on where you need help. For companies wanting to better understand cryo-EM's potential or move rapidly to adopting the technique, we offer bespoke training, where you are free to particpate in and progress real samples along the experimental pipeline with us.